San Francisco @ Philadelphia
Team Totals: 49ers 26.5, Eagles 23.5
Jimmy Garoppolo’s lofty Week 1 passing yards need context; the 49ers faced the lowly Lions – who lost top CB Jeff Okudah to an in-game Achilles’ tear – and Jimmy G’s box-score stats will continue to be threatened by Trey Lance, who replaced him in first-quarter scoring position and hit Trent Sherfield for a five-yard touchdown pass. Week 2 opponent Philadelphia’s pass defense looked formidable on Opening Day, as Eagles DT Javon Hargrave caved in the interior of Atlanta’s offensive line, and Matt Ryan’s 4.69 yards per pass attempt were his fewest since December of 2009. Garoppolo is just a two-quarterback-league play. … Sixth-round rookie RB Elijah Mitchell’s explosive opener gives him first dibs on San Francisco’s lead back job, but neither Trey Sermon nor JaMycal Hasty should be dismissed as going-forward factors in what can be a whimsical backfield under Kyle Shanahan.