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Arizona @ New England
Team Totals: Cardinals 25.75, Patriots 23.75

Coming off a long week to rest his tweaked throwing shoulder following Week 11’s Thursday night loss in Seattle, Kyler Murray takes on a Patriots defense Joe Flacco, Lamar Jackson, and Deshaun Watson set ablaze for a combined 70-of-96 passing (73%), 855 yards (8.9 YPA), and a 7:2 TD-to-INT ratio over its last three games. New England’s pass-rush deficiencies and man-coverage tendencies make Bill Belichick’s team particularly vulnerable to dual-threat quarterbacks, evidenced by its fantasy scores allowed to Russell Wilson (QB4), Jackson (QB7), and Watson (QB1). Through 10 starts, Murray has yet to finish below QB12. He’s banked top-five outcomes in 70% of his games. … Even as Chase Edmonds (54%) out-snapped Kenyan Drake (49%) in last week’s defeat, Drake out-touched Edmonds 15 to 6 and set year highs in targets (5) and receiving (4/31/0) against the Seahawks.

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