Buffalo @ Indianapolis
Team Totals: Bills 26, Colts 22
Fantasy’s overall QB4 on the season, Josh Allen encounters a Colts defense giving up the NFL’s fourth-highest completion rate (70.1%), sixth-most yards per pass attempt (7.8), and eighth-highest QB rating (100.2). Allen’s box-score expectation is enhanced beneath Indy’s Lucas Oil Stadium dome. … James Cook hasn’t reached a 60% playing-time clip in any of his last seven appearances but is averaging 17.5 touches for 101 yards and 1.0 TDs over Buffalo’s last two games, operating as the Bills’ definitive No. 1 back over Ty Johnson and Ray Davis. On the season, Indianapolis is hemorrhaging 157 total yards per game to running backs. Cook is an RB1 play here. Johnson and Davis continue to split RB2 duties.
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