Tennessee @ Indianapolis
Team Totals: Colts 26.5, Titans 25
Titans-Colts is a high-stakes battle between the only two legitimate contenders in the AFC South; neither Jacksonville nor Houston can be taken seriously at this point, while a victory for host Indianapolis would narrow Tennessee’s division lead to one game. In seven meetings since Matt Eberflus took over as Colts defensive coordinator in 2018, Derrick Henry has stampeded Indy for a combined 140/764/5 (5.46 YPC) rushing line and 151-total yards average over these teams’ last four dates. … A top-10 fantasy QB scorer in each of his last two bouts with Eberflus, Ryan Tannehill now draws an Indianapolis defense that has given up the league’s 11th-most fantasy quarterback points, including an AFC-high 16 touchdown passes. The Colts have struggled to rush the QB — foreshadowing clean pockets for Tannehill — while A.J. Brown and Julio Jones both look likely to play. Tannehill should be planted in fantasy lineups as an upside QB1.
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