Arizona @ San Francisco
Team Totals: 49ers 28, Cardinals 21
A to-date fantasy disappointment with finishes of QB15 or worse in three of four starts, Kyler Murray now faces a 49ers defense that has played mediocre pass defense and appears likely to be without All-World ILB Fred Warner (ankle). The good news is Trey McBride (concussion) is due back and San Francisco should pour points all over Arizona’s defense, creating shootout and/or garbage-time scoring opportunities. I’m standing behind Murray as a fantasy QB1 here. … James Conner’s Week 5 matchup will improve if Warner joins DT Javon Hargrave (triceps, I.R.) on the shelf. Conner banked Weeks 1-4 touch counts of 19, 22, 10, and 19, although Emari Demercado’s usage could spike if Arizona falls far behind.
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