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L.A. Rams @ Buffalo
Team Totals: Bills 25, Rams 22.5

The NFC’s run-heaviest team through two weeks, the Rams visit Buffalo with a combined 79-to-58 run-pass ratio in wins over Dallas and Philadelphia. Injuries to Cam Akers (ribs) and Malcolm Brown (pinkie) threaten to throw a wrench into Sean McVay’s approach, however, and visiting Buffalo may further discourage it after the Bills stacked up Jets and Dolphins backs for a combined rushing line of 33/133/2 (4.03 YPC) in Weeks 1-2. Regardless, Darrell Henderson should be rostered in all leagues after erupting for 121 yards on 14 touches in last week’s victory, including an explosive 40-yard, up-the-gut run in the second half and a goal-line TD in the fourth quarter. Henderson left the University of Memphis with one of college football’s best-ever yards-per-carry averages (8.2), and the Rams traded up for him in the 2019 draft.

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