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Indianapolis @ Tennessee

Team Totals: Colts 21.5, Titans 20.5

Out for at least the next 2-3 weeks, Jonathan Taylor’s (thumb) absence thrusts Zack Moss back into Colts bellcow duties after Moss averaged 24 touches for 107.3 yards and 0.7 touchdowns when Taylor missed Weeks 2-4. In Week 5 — Taylor was eased into his 2023 debut — Moss tagged this same Titans defense for 195 total yards, 7.2 yards per carry, and two end-zone trips. One of the NFL’s top running backs this year, Moss is a legitimately elite RB1 play until Taylor returns. … Gardner Minshew’s matchup is theoretically favorable against Tennessee’s pass-funnel defense, yet Minshew has scored below 16 fantasy points in 10 of 11 appearances, and the Titans have allowed the NFL’s 12th-fewest fantasy points to quarterbacks.

Minshew’s 2023 targets: Michael Pittman 89; Josh Downs 60; Alec Pierce 33; Moss 20; Taylor 19; Kylen Granson 17; Will Mallory 11; Isaiah McKenzie and Drew Ogletree 10. … The focal point of Indy’s RPO-dominated passing offense, Pittman has drawn double-digit targets in seven of 11 games and has eight or more catches in four straight entering Week 13.

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