San Francisco @ L.A. Rams
Team Totals: 49ers 25.5, Rams 18.5
Fresh off imposing their will all over the Steelers at Heinz Field, the 49ers’ offense draws a Rams defense that out-coached Week 1 opponent Seattle while preying on injuries to both Seahawks starting offensive tackles. Rams DC Raheem Morris frequently dropped eight into coverage against Seattle, but he won’t be able to repeat versus San Francisco’s humming ground game. Christian McCaffrey logged 85% of the 49ers’ Week 1 running back snaps and 25 of 30 (83%) running back touches en route to 169 total yards and a score. Elijah Mitchell was surprisingly lightly deployed. McCaffrey remains this week’s overall RB1 play, and it’s not particularly close, especially with Austin Ekeler (ankle) in doubt. … Brock Purdy enters Week 2 having thrown two or more TD passes in seven straight regular-season games. Purdy’s rushing impact is minor, and he’s averaging only 27.1 pass attempts in that span, limiting his ceiling. He’s still just a two-quarterback-league starter against a Rams defense that held Geno Smith to Week 1’s QB25 score.
Purdy’s Week 1 target distribution: Brandon Aiyuk 8; Deebo Samuel 7; George Kittle 6; CMC 5; Mitchell and Jauan Jennings 1. … Aiyuk was Purdy’s favorite weapon in the second half of last season, and the two picked back up right where they left off in Week 1 against the Steelers. Dog walking pregame trash talker Patrick Peterson relentlessly, Aiyuk also endeared himself to Kyle Shanahan’s coaching staff with an ass-kicking open-field block on McCaffrey’s 65-yard touchdown run. I’m locking in Aiyuk as an every-week WR2 starter. … Deebo’s Opening Day box score was mild, but he still banked seven touches and can deliver an eruption game at any moment. … Kittle drew six Week 1 targets after seeing more than six targets in only four of 18 games (including playoffs) last season. Monster weeks are on the docket for Kittle.
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